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Crystal structure of TcpK in complex with oriT DNA of the antibiotic resistance plasmid pCW3
Conjugation is fundamental for the acquisition of new genetic traits and the development of antibiotic resistance in pathogenic organisms. Here, we show that a hypothetical Clostridium perfringens protein, TcpK, which is encoded by the tetracycline resistance plasmid pCW3, is essential for efficient...
Autores principales: | Traore, Daouda A. K., Wisniewski, Jessica A., Flanigan, Sarena F., Conroy, Paul J., Panjikar, Santosh, Mok, Yee-Foong, Lao, Carmen, Griffin, Michael D. W., Adams, Vicki, Rood, Julian I., Whisstock, James C. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6137059/ https://www.ncbi.nlm.nih.gov/pubmed/30213934 http://dx.doi.org/10.1038/s41467-018-06096-2 |
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