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FACT Sets a Barrier for Cell Fate Reprogramming in Caenorhabditis elegans and Human Cells
The chromatin regulator FACT (facilitates chromatin transcription) is essential for ensuring stable gene expression by promoting transcription. In a genetic screen using Caenorhabditis elegans, we identified that FACT maintains cell identities and acts as a barrier for transcription factor-mediated...
Autores principales: | , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cell Press
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6137076/ https://www.ncbi.nlm.nih.gov/pubmed/30078731 http://dx.doi.org/10.1016/j.devcel.2018.07.006 |