Missense mutation of VKORC1 leads to medial arterial calcification in rats

Vitamin K plays a crucial role in the regulation of vascular calcifications by allowing activation of matrix Gla protein. The dietary requirement for vitamin K is low because of an efficient recycling of vitamin K by vitamin K epoxide reductase (VKORC1). However, decreased VKORC1 activity may result...

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Detalles Bibliográficos
Autores principales: Michaux, Arnaud, Matagrin, Benjamin, Debaux, Jean-Valéry, Schurgers, Leon J., Benoit, Etienne, Lattard, Virginie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6137107/
https://www.ncbi.nlm.nih.gov/pubmed/30214074
http://dx.doi.org/10.1038/s41598-018-31788-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6137107/
https://www.ncbi.nlm.nih.gov/pubmed/30214074
http://dx.doi.org/10.1038/s41598-018-31788-6

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