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X-ray structure of full-length human RuvB-Like 2 – mechanistic insights into coupling between ATP binding and mechanical action

RuvB-Like transcription factors function in cell cycle regulation, development and human disease, such as cancer and heart hyperplasia. The mechanisms that regulate adenosine triphosphate (ATP)-dependent activity, oligomerization and post-translational modifications in this family of enzymes are yet...

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Detalles Bibliográficos
Autores principales: Silva, Sara T. N., Brito, José A., Arranz, Rocío, Sorzano, Carlos Óscar S., Ebel, Christine, Doutch, James, Tully, Mark D., Carazo, José-María, Carrascosa, José L., Matias, Pedro M., Bandeiras, Tiago M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6137109/
https://www.ncbi.nlm.nih.gov/pubmed/30213962
http://dx.doi.org/10.1038/s41598-018-31997-z