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Noninvasive assessment of characteristics of novel anti-HER2 antibodies by molecular imaging in a human gastric cancer xenograft-bearing mouse model

Human epidermal growth factor receptor 2 (HER2) overexpression occurs in various types of cancers. Regarding the anti-HER2 targeted therapies showed superior treatment outcomes in several (pre)clinical studies, we used multimodality image to rapidly select novel HER2-targeting antibodies for further...

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Detalles Bibliográficos
Autores principales: Kuo, Wei-Ying, Lin, Jia-Jia, Hsu, Hung-Ju, Chen, Hong-Sen, Yang, An-Suei, Wu, Chun-Yi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6137128/
https://www.ncbi.nlm.nih.gov/pubmed/30214017
http://dx.doi.org/10.1038/s41598-018-32094-x