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A small molecule targeting myoferlin exerts promising anti-tumor effects on breast cancer

Breast cancer is one of the most lethal cancers in women when it reaches the metastatic stage. Here, we screen a library of small molecules for inhibitors of breast cancer cell invasion, and use structure/activity relationship studies to develop a series of small molecules with improved activity. We...

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Detalles Bibliográficos
Autores principales: Zhang, Tao, Li, Jingjie, He, Yuan, Yang, Feifei, Hao, Yun, Jin, Wangrui, Wu, Jing, Sun, Zhenliang, Li, Yunqi, Chen, Yihua, Yi, Zhengfang, Liu, Mingyao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6137146/
https://www.ncbi.nlm.nih.gov/pubmed/30213946
http://dx.doi.org/10.1038/s41467-018-06179-0