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A small molecule targeting myoferlin exerts promising anti-tumor effects on breast cancer
Breast cancer is one of the most lethal cancers in women when it reaches the metastatic stage. Here, we screen a library of small molecules for inhibitors of breast cancer cell invasion, and use structure/activity relationship studies to develop a series of small molecules with improved activity. We...
Autores principales: | , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6137146/ https://www.ncbi.nlm.nih.gov/pubmed/30213946 http://dx.doi.org/10.1038/s41467-018-06179-0 |