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Esters of levonorgestrel and etonogestrel intended as single, subcutaneous-injection, long-lasting contraceptives

An effort with the goal of discovering single-dose, long-lasting (>6 months) injectable contraceptives began using levonorgestrel (LNG)-17-β esters linked to a sulfonamide function purposed as human carbonic anhydrase II (hCA 2) ligands. One single analog from this first series showed noticeably...

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Detalles Bibliográficos
Autores principales: Meece, Frederick A., Ahmed, Gulzar, Nair, Hareesh, Santhamma, Bindu, Tekmal, Rajeshwar R., Zhao, Chumang, Pollok, Nicole E., Lara, Julia, Shaked, Ze'ev, Nickisch, Klaus
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6137153/
https://www.ncbi.nlm.nih.gov/pubmed/30086356
http://dx.doi.org/10.1016/j.steroids.2018.07.010