RNA-Seq Analysis of Spinal Cord Tissues from hPFN1(G118V) Transgenic Mouse Model of ALS at Pre-symptomatic and End-Stages of Disease

Amyotrophic lateral sclerosis (ALS) is a fatal neurodegenerative disease that leads to the loss of motor neurons. The molecular mechanisms of motor neuron degeneration are largely unknown and there are currently no effective therapies to treat this disease. In this work, we report whole transcriptom...

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Detalles Bibliográficos
Autores principales: Barham, Caroline, Fil, Daniel, Byrum, Stephanie D., Rahmatallah, Yasir, Glazko, Galina, Kiaei, Mahmoud
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6137178/
https://www.ncbi.nlm.nih.gov/pubmed/30213953
http://dx.doi.org/10.1038/s41598-018-31132-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6137178/
https://www.ncbi.nlm.nih.gov/pubmed/30213953
http://dx.doi.org/10.1038/s41598-018-31132-y

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