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RNA-Seq Analysis of Spinal Cord Tissues from hPFN1(G118V) Transgenic Mouse Model of ALS at Pre-symptomatic and End-Stages of Disease
Amyotrophic lateral sclerosis (ALS) is a fatal neurodegenerative disease that leads to the loss of motor neurons. The molecular mechanisms of motor neuron degeneration are largely unknown and there are currently no effective therapies to treat this disease. In this work, we report whole transcriptom...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Nature Publishing Group UK
2018
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6137178/ https://www.ncbi.nlm.nih.gov/pubmed/30213953 http://dx.doi.org/10.1038/s41598-018-31132-y |