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METRNL attenuates lipid-induced inflammation and insulin resistance via AMPK or PPARδ-dependent pathways in skeletal muscle of mice

Physical activity has many beneficial effects on metabolic disorders, such as obesity, insulin resistance, and diabetes. Meteorin-like protein (METRNL), a novel secreted protein homologous to the neurotrophin Metrn, is induced after exercise in the skeletal muscle. Herein, we investigated the effect...

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Detalles Bibliográficos
Autores principales: Jung, Tae Woo, Lee, Sung Hoon, Kim, Hyoung-Chun, Bang, Joon Seok, Abd El-Aty, A. M., Hacımüftüoğlu, Ahmet, Shin, Yong Kyoo, Jeong, Ji Hoon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6137187/
https://www.ncbi.nlm.nih.gov/pubmed/30213948
http://dx.doi.org/10.1038/s12276-018-0147-5