Exploring the Ligand Efficacy of Cannabinoid Receptor 1 (CB1) using Molecular Dynamics Simulations

Cannabinoid receptor 1 (CB1) is a promising therapeutic target for a variety of disorders. Distinct efficacy profiles showed different therapeutic effects on CB1 dependent on three classes of ligands: agonists, antagonists, and inverse agonists. To discriminate the distinct efficacy profiles of the...

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Detalles Bibliográficos
Autores principales: Jung, Sang Won, Cho, Art E., Yu, Wookyung
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6137198/
https://www.ncbi.nlm.nih.gov/pubmed/30213978
http://dx.doi.org/10.1038/s41598-018-31749-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6137198/
https://www.ncbi.nlm.nih.gov/pubmed/30213978
http://dx.doi.org/10.1038/s41598-018-31749-z

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