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24S-Hydroxycholesterol Correlates With Tau and Is Increased in Cerebrospinal Fluid in Parkinson's Disease and Corticobasal Syndrome

24S-hydroxycholesterol (24OHC) and Tau are produced in neuronal cells and neurodegeneration leads to increased flux of both of them into cerebrospinal fluid (CSF). In the present study, CSF levels of 24OHC and 27S-hydroxycholesterol (27OHC) along with those of Tau, P-Thr(181)-Tau and Aβ(42) were mea...

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Detalles Bibliográficos
Autores principales: Björkhem, Ingemar, Patra, Kalicharan, Boxer, Adam L., Svenningsson, Per
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6137204/
https://www.ncbi.nlm.nih.gov/pubmed/30245667
http://dx.doi.org/10.3389/fneur.2018.00756