Rapid functional genetics of the oligodendrocyte lineage using pluripotent stem cells

Oligodendrocyte dysfunction underlies many neurological disorders, but rapid assessment of mutation-specific effects in these cells has been impractical. To enable functional genetics in oligodendrocytes, here we report a highly efficient method for generating oligodendrocytes and their progenitors...

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Detalles Bibliográficos
Autores principales: Lager, Angela M., Corradin, Olivia G., Cregg, Jared M., Elitt, Matthew S., Shick, H. Elizabeth, Clayton, Benjamin L. L., Allan, Kevin C., Olsen, Hannah E., Madhavan, Mayur, Tesar, Paul J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6137209/
https://www.ncbi.nlm.nih.gov/pubmed/30213958
http://dx.doi.org/10.1038/s41467-018-06102-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6137209/
https://www.ncbi.nlm.nih.gov/pubmed/30213958
http://dx.doi.org/10.1038/s41467-018-06102-7

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