Histone H3K9 demethylase JMJD2B induces hepatic steatosis through upregulation of PPARγ2

Understanding the epigenetic mechanisms underlying the progression of hepatic steatosis is important for identifying new therapeutic targets against nonalcoholic fatty liver disease (NAFLD). We investigated the functional role of histone demethylase JMJD2B in the pathologic regulation of hepatic ste...

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Detalles Bibliográficos
Autores principales: Kim, Ji-Hyun, Jung, Dae Young, Nagappan, Arulkumar, Jung, Myeong Ho
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6137221/
https://www.ncbi.nlm.nih.gov/pubmed/30214048
http://dx.doi.org/10.1038/s41598-018-31953-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6137221/
https://www.ncbi.nlm.nih.gov/pubmed/30214048
http://dx.doi.org/10.1038/s41598-018-31953-x

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