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Mean-Independent Noise Control of Cell Fates via Intermediate States

Stochasticity affects accurate signal detection and robust generation of correct cell fates. Although many known regulatory mechanisms may reduce fluctuations in signals, most simultaneously influence their mean dynamics, leading to unfaithful cell fates. Through analysis and computation, we demonst...

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Detalles Bibliográficos
Autores principales: Rackauckas, Christopher, Schilling, Thomas, Nie, Qing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6137274/
https://www.ncbi.nlm.nih.gov/pubmed/30428314
http://dx.doi.org/10.1016/j.isci.2018.04.002