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Understanding How Wnt Influences Destruction Complex Activity and β-Catenin Dynamics
Despite extensive research on the canonical Wnt signaling pathway, the mechanism by which this signal downregulates the activity of destruction complexes and inhibits β-catenin degradation remains controversial. In particular, recent attention has focused on two main competing mechanisms—inhibition...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Elsevier
2018
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6137275/ https://www.ncbi.nlm.nih.gov/pubmed/30240607 http://dx.doi.org/10.1016/j.isci.2018.07.007 |