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Coupling of DNA Replication and Negative Feedback Controls Gene Expression for Cell-Fate Decisions

Cellular decision-making arises from the expression of genes along a regulatory cascade, which leads to a choice between distinct phenotypic states. DNA dosage variations, often introduced by replication, can significantly affect gene expression to ultimately bias decision outcomes. The bacteriophag...

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Detalles Bibliográficos
Autores principales: Shao, Qiuyan, Cortes, Michael G., Trinh, Jimmy T., Guan, Jingwen, Balázsi, Gábor, Zeng, Lanying
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6137276/
https://www.ncbi.nlm.nih.gov/pubmed/30240603
http://dx.doi.org/10.1016/j.isci.2018.07.006