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Lopinavir, an HIV-1 peptidase inhibitor, induces alteration on the lipid metabolism of Leishmania amazonensis promastigotes

The anti-leishmania effects of HIV peptidase inhibitors (PIs) have been widely reported; however, the biochemical target and mode of action are still a matter of controversy in Leishmania parasites. Considering the possibility that HIV-PIs induce lipid accumulation in Leishmania amazonensis, we anal...

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Detalles Bibliográficos
Autores principales: Rebello, Karina M., Andrade-Neto, Valter V., Zuma, Aline A., Motta, Maria Cristina M., Gomes, Claudia Regina B., de Souza, Marcus Vinícius N., Atella, Geórgia C., Branquinha, Marta H., Santos, André L. S., Torres-Santos, Eduardo Caio, d'Avila-Levy, Claudia M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cambridge University Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6137378/
https://www.ncbi.nlm.nih.gov/pubmed/29806577
http://dx.doi.org/10.1017/S0031182018000823