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In Mitochondria β-Actin Regulates mtDNA Transcription and Is Required for Mitochondrial Quality Control
In eukaryotic cells, actin regulates both cytoplasmic and nuclear functions. However, whether actin-based structures are present in the mitochondria and are involved in mitochondrial functions has not been investigated. Here, using wild-type β-actin +/+ and knockout (KO) β-actin −/− mouse embryonic...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6137402/ https://www.ncbi.nlm.nih.gov/pubmed/30428323 http://dx.doi.org/10.1016/j.isci.2018.04.021 |