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A Comprehensive Mutagenesis Screen of the Adhesion GPCR Latrophilin-1/ADGRL1

Adhesion G-protein-coupled receptors (aGPCRs) play critical roles in diverse cellular processes in neurobiology, development, immunity, and numerous diseases. The lack of molecular understanding of their activation mechanisms, especially with regard to the transmembrane domains, hampers further stud...

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Detalles Bibliográficos
Autores principales: Nazarko, Olha, Kibrom, Amanuel, Winkler, Jana, Leon, Katherine, Stoveken, Hannah, Salzman, Gabriel, Merdas, Katarzyna, Lu, Yue, Narkhede, Pradnya, Tall, Gregory, Prömel, Simone, Araç, Demet
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6137404/
https://www.ncbi.nlm.nih.gov/pubmed/30428326
http://dx.doi.org/10.1016/j.isci.2018.04.019