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Variation in RAD51 details a hub of functions: opportunities to advance cancer diagnosis and therapy

Loss of genome stability is one of the hallmarks of the enabling characteristics of cancer development. Homologous recombination is a DNA repair process that often breaks down as a prelude to developing cancer. Conversely, homologous recombination can be the Achilles’ heel in common anti-cancer ther...

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Detalles Bibliográficos
Autores principales: van der Zon, Nick LL, Kanaar, Roland, Wyman, Claire
Formato: Online Artículo Texto
Lenguaje:English
Publicado: F1000 Research Limited 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6137408/
https://www.ncbi.nlm.nih.gov/pubmed/30271574
http://dx.doi.org/10.12688/f1000research.15650.2