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Variation in RAD51 details a hub of functions: opportunities to advance cancer diagnosis and therapy
Loss of genome stability is one of the hallmarks of the enabling characteristics of cancer development. Homologous recombination is a DNA repair process that often breaks down as a prelude to developing cancer. Conversely, homologous recombination can be the Achilles’ heel in common anti-cancer ther...
Autores principales: | van der Zon, Nick LL, Kanaar, Roland, Wyman, Claire |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
F1000 Research Limited
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6137408/ https://www.ncbi.nlm.nih.gov/pubmed/30271574 http://dx.doi.org/10.12688/f1000research.15650.2 |
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