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Tuning the reactivity of nitriles using Cu(ii) catalysis – potentially prebiotic activation of nucleotides
During the transition from prebiotic chemistry to biology, a period of solution-phase, non-enzymatic activation of (oligo)nucleotides must have occurred, and accordingly, a mechanism for phosphate activation must have existed. Herein, we detail results of an investigation into prebiotic phosphate ac...
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Royal Society of Chemistry
2018
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6137443/ https://www.ncbi.nlm.nih.gov/pubmed/30310625 http://dx.doi.org/10.1039/c8sc02513d |