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The ATP Transporter VNUT Mediates Induction of Dectin-1-Triggered Candida Nociception

Candida albicans infection can cause skin, vulvar, or oral pain. Despite the obvious algesic activity of C. albicans, the molecular mechanisms of fungal nociception remain largely unknown. Here we show that the C. albicans-specific signaling pathway led to severe mechanical allodynia. We discovered...

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Detalles Bibliográficos
Autores principales: Maruyama, Kenta, Takayama, Yasunori, Sugisawa, Erika, Yamanoi, Yu, Yokawa, Takashi, Kondo, Takeshi, Ishibashi, Ken-ichi, Sahoo, Bikash Ranjan, Takemura, Naoki, Mori, Yuki, Kanemaru, Hisashi, Kumagai, Yutaro, Martino, Mikaël M., Yoshioka, Yoshichika, Nishijo, Hisao, Tanaka, Hiroki, Sasaki, Atsushi, Ohno, Naohito, Iwakura, Yoichiro, Moriyama, Yoshinori, Nomura, Masatoshi, Akira, Shizuo, Tominaga, Makoto
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6137711/
https://www.ncbi.nlm.nih.gov/pubmed/30240621
http://dx.doi.org/10.1016/j.isci.2018.08.007