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The ATP Transporter VNUT Mediates Induction of Dectin-1-Triggered Candida Nociception
Candida albicans infection can cause skin, vulvar, or oral pain. Despite the obvious algesic activity of C. albicans, the molecular mechanisms of fungal nociception remain largely unknown. Here we show that the C. albicans-specific signaling pathway led to severe mechanical allodynia. We discovered...
Autores principales: | Maruyama, Kenta, Takayama, Yasunori, Sugisawa, Erika, Yamanoi, Yu, Yokawa, Takashi, Kondo, Takeshi, Ishibashi, Ken-ichi, Sahoo, Bikash Ranjan, Takemura, Naoki, Mori, Yuki, Kanemaru, Hisashi, Kumagai, Yutaro, Martino, Mikaël M., Yoshioka, Yoshichika, Nishijo, Hisao, Tanaka, Hiroki, Sasaki, Atsushi, Ohno, Naohito, Iwakura, Yoichiro, Moriyama, Yoshinori, Nomura, Masatoshi, Akira, Shizuo, Tominaga, Makoto |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6137711/ https://www.ncbi.nlm.nih.gov/pubmed/30240621 http://dx.doi.org/10.1016/j.isci.2018.08.007 |
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