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Nck1 Deficiency Impairs Adipogenesis by Activation of PDGFRα in Preadipocytes
Obesity results from an excessive expansion of white adipose tissue (WAT), which is still poorly understood from an etiologic-mechanistic perspective. Here, we report that Nck1, a Src homology domain-containing adaptor, is upregulated during WAT expansion and in vitro adipogenesis. In agreement, Nck...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6137712/ https://www.ncbi.nlm.nih.gov/pubmed/30240612 http://dx.doi.org/10.1016/j.isci.2018.07.010 |