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Control of directionality of chromatin folding for the inter- and intra-domain contacts at the Tfap2c–Bmp7 locus

BACKGROUND: Contact domains of chromatin serve as a fundamental unit to regulate action of enhancers for target genes. Looping between a pair of CCCTC-binding factor (CTCF)-binding sites in convergent orientations underlies the formation of contact domains, while those in divergent orientations esta...

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Detalles Bibliográficos
Autores principales: Tsujimura, Taro, Takase, Osamu, Yoshikawa, Masahiro, Sano, Etsuko, Hayashi, Matsuhiko, Takato, Tsuyoshi, Toyoda, Atsushi, Okano, Hideyuki, Hishikawa, Keiichi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6137755/
https://www.ncbi.nlm.nih.gov/pubmed/30213272
http://dx.doi.org/10.1186/s13072-018-0221-1