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Triglycerides Promote Lipid Homeostasis during Hypoxic Stress by Balancing Fatty Acid Saturation

Lipid droplets, which store triglycerides and cholesterol esters, are a prominent feature of clear cell renal cell carcinoma (ccRCC). Although their presence in ccRCC is critical for sustained tumorigenesis, their contribution to lipid homeostasis and tumor cell viability is incompletely understood....

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Detalles Bibliográficos
Autores principales: Ackerman, Daniel, Tumanov, Sergey, Qiu, Bo, Michalopoulou, Evdokia, Spata, Michelle, Azzam, Andrew, Xie, Hong, Simon, M. Celeste, Kamphorst, Jurre J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6137821/
https://www.ncbi.nlm.nih.gov/pubmed/30184495
http://dx.doi.org/10.1016/j.celrep.2018.08.015