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Triglycerides Promote Lipid Homeostasis during Hypoxic Stress by Balancing Fatty Acid Saturation
Lipid droplets, which store triglycerides and cholesterol esters, are a prominent feature of clear cell renal cell carcinoma (ccRCC). Although their presence in ccRCC is critical for sustained tumorigenesis, their contribution to lipid homeostasis and tumor cell viability is incompletely understood....
Autores principales: | Ackerman, Daniel, Tumanov, Sergey, Qiu, Bo, Michalopoulou, Evdokia, Spata, Michelle, Azzam, Andrew, Xie, Hong, Simon, M. Celeste, Kamphorst, Jurre J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cell Press
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6137821/ https://www.ncbi.nlm.nih.gov/pubmed/30184495 http://dx.doi.org/10.1016/j.celrep.2018.08.015 |
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