Eremomycin pyrrolidide: a novel semisynthetic glycopeptide with improved chemotherapeutic properties

PURPOSE: Development of new semisynthetic glycopeptides with improved antibacterial efficacy and reduced pseudoallergic reactions. METHODS: Semisynthetic glycopeptides 3–6 were synthesized from vancomycin (1) or eremomycin (2) by the condensation with pyrrolidine or piperidine. The minimum inhibitor...

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Detalles Bibliográficos
Autores principales: Olsufyeva, Evgenia N, Shchekotikhin, Andrey E, Bychkova, Elena N, Pereverzeva, Eleonora R, Treshalin, Ivan D, Mirchink, Elena P, Isakova, Elena B, Chernobrovkin, Mikhail G, Kozlov, Roman S, Dekhnich, Andrey V, Preobrazhenskaya, Maria N
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2018
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6137948/
https://www.ncbi.nlm.nih.gov/pubmed/30237697
http://dx.doi.org/10.2147/DDDT.S173923

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6137948/
https://www.ncbi.nlm.nih.gov/pubmed/30237697
http://dx.doi.org/10.2147/DDDT.S173923

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