3-Chloro-N′-(2-hydroxybenzylidene) benzohydrazide: An LSD1-Selective Inhibitor and Iron-Chelating Agent for Anticancer Therapy

Despite the discovery and development of novel therapies, cancer is still a leading cause of death worldwide. In order to grow, tumor cells require large quantities of nutrients involved in metabolic processes, and an increase in iron levels is known to contribute to cancer proliferation. Iron plays...

Descripción completa

Detalles Bibliográficos
Autores principales: Sarno, Federica, Papulino, Chiara, Franci, Gianluigi, Andersen, Jeanette H., Cautain, Bastien, Melardo, Colombina, Altucci, Lucia, Nebbioso, Angela
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6137965/
https://www.ncbi.nlm.nih.gov/pubmed/30245629
http://dx.doi.org/10.3389/fphar.2018.01006

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6137965/
https://www.ncbi.nlm.nih.gov/pubmed/30245629
http://dx.doi.org/10.3389/fphar.2018.01006

Ejemplares similares