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3-Chloro-N′-(2-hydroxybenzylidene) benzohydrazide: An LSD1-Selective Inhibitor and Iron-Chelating Agent for Anticancer Therapy
Despite the discovery and development of novel therapies, cancer is still a leading cause of death worldwide. In order to grow, tumor cells require large quantities of nutrients involved in metabolic processes, and an increase in iron levels is known to contribute to cancer proliferation. Iron plays...
Autores principales: | Sarno, Federica, Papulino, Chiara, Franci, Gianluigi, Andersen, Jeanette H., Cautain, Bastien, Melardo, Colombina, Altucci, Lucia, Nebbioso, Angela |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6137965/ https://www.ncbi.nlm.nih.gov/pubmed/30245629 http://dx.doi.org/10.3389/fphar.2018.01006 |
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