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Synthesis-dependent repair of Cpf1-induced double strand DNA breaks enables targeted gene replacement in rice
The recently developed CRISPR (clustered regularly interspaced short palindromic repeats)/Cpf1 system expands the range of genome editing and is emerging as an alternative powerful tool for both plant functional genomics and crop improvement. Cpf1-CRISPR RNA (crRNA) produces double strand DNA breaks...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6137971/ https://www.ncbi.nlm.nih.gov/pubmed/29955893 http://dx.doi.org/10.1093/jxb/ery245 |