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Synthesis-dependent repair of Cpf1-induced double strand DNA breaks enables targeted gene replacement in rice

The recently developed CRISPR (clustered regularly interspaced short palindromic repeats)/Cpf1 system expands the range of genome editing and is emerging as an alternative powerful tool for both plant functional genomics and crop improvement. Cpf1-CRISPR RNA (crRNA) produces double strand DNA breaks...

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Detalles Bibliográficos
Autores principales: Li, Shaoya, Li, Jingying, Zhang, Jiahui, Du, Wenming, Fu, Jindong, Sutar, Suhas, Zhao, Yunde, Xia, Lanqin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6137971/
https://www.ncbi.nlm.nih.gov/pubmed/29955893
http://dx.doi.org/10.1093/jxb/ery245