TiSAn: estimating tissue-specific effects of coding and non-coding variants

MOTIVATION: Model-based estimates of general deleteriousness, like CADD, DANN or PolyPhen, have become indispensable tools in the interpretation of genetic variants. However, these approaches say little about the tissues in which the effects of deleterious variants will be most meaningful. Tissue-sp...

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Detalles Bibliográficos
Autores principales: Vervier, Kévin, Michaelson, Jacob J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2018
Materias:
Discovery Note
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6137979/
https://www.ncbi.nlm.nih.gov/pubmed/29912365
http://dx.doi.org/10.1093/bioinformatics/bty301

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6137979/
https://www.ncbi.nlm.nih.gov/pubmed/29912365
http://dx.doi.org/10.1093/bioinformatics/bty301

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