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Optimization of episomal reprogramming for generation of human induced pluripotent stem cells from fibroblasts
Generation of induced pluripotent stem cells (iPSCs) by defined factors (OCT4, SOX2, C-MYC, and KLF4) from various human primary cells has been reported. Human fibroblasts have been widely used as a cellular source in reprogramming studies over recent decades. The original method of iPSC generation...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Taylor & Francis
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6138300/ https://www.ncbi.nlm.nih.gov/pubmed/30460090 http://dx.doi.org/10.1080/19768354.2018.1451367 |