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Phenotypic differences between Drosophila Alzheimer’s disease models expressing human Aβ42 in the developing eye and brain

Drosophila melanogaster expressing amyloid-β42 (Aβ42) transgenes have been used as models to study Alzheimer’s disease. Various Aβ42 transgenes with different structures induce different phenotypes, which make it difficult to compare data among studies which use different transgenic lines. In this s...

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Detalles Bibliográficos
Autores principales: Jeon, Youngjae, Lee, Soojin, Shin, Myoungchul, Lee, Jang Ho, Suh, Yoon Seok, Hwang, Soojin, Yun, Hye Sup, Cho, Kyoung Sang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6138326/
https://www.ncbi.nlm.nih.gov/pubmed/30460065
http://dx.doi.org/10.1080/19768354.2017.1313777