Autophagy mediates SUMO-induced degradation of a polyglutamine protein ataxin-3

Previously, we reported that small ubiquitin-like modifier-1 (SUMO-1) promotes the degradation of a polyglutamine (polyQ) protein ataxin-3 and proposed that proteasomes mediate the proteolysis. Here, we present evidence that autophagy is also responsible for SUMO-induced degradation of this polyQ pr...

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Detalles Bibliográficos
Autores principales: Hwang, Soo Pyung, Lee, Do Hee
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2017
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6138331/
https://www.ncbi.nlm.nih.gov/pubmed/30460066
http://dx.doi.org/10.1080/19768354.2017.1330765

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6138331/
https://www.ncbi.nlm.nih.gov/pubmed/30460066
http://dx.doi.org/10.1080/19768354.2017.1330765

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