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Autophagy mediates SUMO-induced degradation of a polyglutamine protein ataxin-3
Previously, we reported that small ubiquitin-like modifier-1 (SUMO-1) promotes the degradation of a polyglutamine (polyQ) protein ataxin-3 and proposed that proteasomes mediate the proteolysis. Here, we present evidence that autophagy is also responsible for SUMO-induced degradation of this polyQ pr...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Taylor & Francis
2017
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6138331/ https://www.ncbi.nlm.nih.gov/pubmed/30460066 http://dx.doi.org/10.1080/19768354.2017.1330765 |