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Induction of telomere shortening and cellular apoptosis by sodium meta-arsenite in human cancer cell lines

The present study assessed the cytotoxicity of sodium meta-arsenite (SMA) on telomere shortening and cellular apoptosis in human A-549, MDA-MB-231 and U87-MG cancer cell lines. Following 2 weeks of 1 μM SMA treatment, population doubling time (PDT) was significantly (P < .05) increased by the inh...

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Detalles Bibliográficos
Autores principales: Kim, Yoon-Dong, Jang, Si-Jeong, Lim, Eun-Ji, Ha, Jeong-Sook, Shivakumar, Sharath Belame, Jeong, Gie-Joon, Rho, Gyu-Jin, Jeon, Byeong-Gyun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6138346/
https://www.ncbi.nlm.nih.gov/pubmed/30460075
http://dx.doi.org/10.1080/19768354.2017.1342691