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Generation of motor neurons requires spatiotemporal coordination between retinoic acid and Mib-mediated Notch signaling

Mind bomb (Mib) is an E3 ubiquitin ligase that activates the Notch signaling pathway. A previous study demonstrated that the generation of late-born GABAergic neurons may be regulated by the interplay between Mib and retinoic acid (RA). However, the relationship between Mib function and the retinoid...

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Detalles Bibliográficos
Autores principales: Kong, Hee Jeong, Ryu, Jae-Ho, Kim, Julan, Kim, Ju-Won, Seong, Bomi, Whang, Ilson, Park, Jung Youn, Yeo, Sang-Yeob
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6138348/
https://www.ncbi.nlm.nih.gov/pubmed/30460083
http://dx.doi.org/10.1080/19768354.2018.1443494