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Induction of obesity impairs reverse cholesterol transport in ob/ob mice

OBJECTIVES: Obesity is an independent risk factor for cardiovascular disease. Reverse cholesterol transport (RCT) is an important cardioprotective mechanism. This study aimed to investigate RCT changes in a murine model of obesity. METHODS: Ob/ob and control mice were injected with [(3)H]-cholestero...

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Detalles Bibliográficos
Autores principales: Duong, MyNgan, Uno, Kiyoko, Nankivell, Victoria, Bursill, Christina, Nicholls, Stephen J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6138368/
https://www.ncbi.nlm.nih.gov/pubmed/30216355
http://dx.doi.org/10.1371/journal.pone.0202102