Stimulation of transforming growth factor-beta-1 and contact with type I collagen cooperatively facilitate irreversible transdifferentiation in proximal tubular cells

BACKGROUND: By transdifferentiation, proximal tubular cells (PTC) have been considered as a source of interstitial myofibroblasts. We examined the combined effect of transforming growth factor-beta-1 (TGF-β1) stimulation and contact with type I collagen on PTC transdifferentiation. METHODS: Human ki...

Descripción completa

Detalles Bibliográficos
Autores principales: Yen, Chieh-Li, Li, Yi-Jung, Wu, Hsin-Hsu, Weng, Cheng-Hao, Lee, Cheng-Chia, Chen, Yung-Chang, Chang, Ming-Yang, Yen, Tzung-Hai, Hsu, Hsiang-Hao, Hung, Cheng-Chieh, Yang, Chih-Wei, Tian, Ya-Chung
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Chang Gung University 2016
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6138427/
https://www.ncbi.nlm.nih.gov/pubmed/27105597
http://dx.doi.org/10.1016/j.bj.2015.08.004

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6138427/
https://www.ncbi.nlm.nih.gov/pubmed/27105597
http://dx.doi.org/10.1016/j.bj.2015.08.004

Ejemplares similares