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Development of sensitive ddPCR assays to reliably quantify the proviral DNA reservoir in all common circulating HIV subtypes and recombinant forms
INTRODUCTION: The latent reservoir is the main barrier on the road to HIV cure, and clinical approaches towards eradication are often evaluated by their effect on proviral DNA. To ensure inclusiveness and representativeness in HIV cure studies, proviral DNA quantification assays that are able to det...
Autores principales: | Bosman, Kobus J, Wensing, Annemarie MJ, Pijning, Aster E, van Snippenberg, Wilco J, van Ham, Petra M, de Jong, Dorien MC, Hoepelman, Andy IM, Nijhuis, Monique |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6138437/ https://www.ncbi.nlm.nih.gov/pubmed/30375818 http://dx.doi.org/10.1002/jia2.25185 |
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