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Effect of single and multiple doses of elobixibat, an ileal bile acid transporter inhibitor, on chronic constipation: A randomized controlled trial

AIMS: Elobixibat is a minimally absorbed ileal bile acid transporter inhibitor. This study aimed to investigate the safety, tolerability, efficacy, pharmacokinetics and pharmacodynamics of elobixibat in Japanese patients with chronic constipation. METHODS: This study consisted of single‐dose and mul...

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Detalles Bibliográficos
Autores principales: Kumagai, Yuji, Amano, Hideki, Sasaki, Yoshinobu, Nakagawa, Chie, Maeda, Mika, Oikawa, Ichiro, Furuie, Hidetoshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6138487/
https://www.ncbi.nlm.nih.gov/pubmed/29959787
http://dx.doi.org/10.1111/bcp.13698