Cargando…
Effect of single and multiple doses of elobixibat, an ileal bile acid transporter inhibitor, on chronic constipation: A randomized controlled trial
AIMS: Elobixibat is a minimally absorbed ileal bile acid transporter inhibitor. This study aimed to investigate the safety, tolerability, efficacy, pharmacokinetics and pharmacodynamics of elobixibat in Japanese patients with chronic constipation. METHODS: This study consisted of single‐dose and mul...
Autores principales: | Kumagai, Yuji, Amano, Hideki, Sasaki, Yoshinobu, Nakagawa, Chie, Maeda, Mika, Oikawa, Ichiro, Furuie, Hidetoshi |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2018
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6138487/ https://www.ncbi.nlm.nih.gov/pubmed/29959787 http://dx.doi.org/10.1111/bcp.13698 |
Ejemplares similares
-
Impact of elobixibat on serum and fecal bile acid levels and constipation symptoms in patients with chronic constipation
por: Nakajima, Atsushi, et al.
Publicado: (2022) -
Safety and Efficacy of Elobixibat, an Ileal Bile Acid Transporter Inhibitor, in Elderly Patients With Chronic Idiopathic Constipation According to Administration Time: Interim Analysis of Post-marketing Surveillance
por: Nakajima, Atsushi, et al.
Publicado: (2022) -
Investigating the efficacy and safety of elobixibat, an ileal bile acid transporter inhibitor, in patients with Parkinson’s disease with chronic constipation: a multicentre, placebo-controlled, randomised, double-blind, parallel-group study (CONST-PD)
por: Hatano, Taku, et al.
Publicado: (2022) -
Determining an optimal clinical dose of elobixibat, a novel inhibitor of the ileal bile acid transporter, in Japanese patients with chronic constipation: a phase II, multicenter, double-blind, placebo-controlled randomized clinical trial
por: Nakajima, Atsushi, et al.
Publicado: (2017) -
Elobixibat alleviates chronic constipation in hemodialysis patients: a questionnaire-based study
por: Kamei, Daigo, et al.
Publicado: (2020)