Coadministration of probenecid and cimetidine with mirogabalin in healthy subjects: A phase 1, randomized, open‐label, drug–drug interaction study

AIMS: The primary aim of this study was to assess the individual effects of probenecid and cimetidine on mirogabalin exposure. METHODS: This phase 1, open‐label, crossover study randomized healthy adults to receive three treatment regimens, each separated by ≥5‐day washout: a single oral dose of mir...

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Detalles Bibliográficos
Autores principales: Tachibana, Masaya, Yamamura, Naotoshi, Atiee, George J., Hsu, Ching, Warren, Vance, He, Ling, Dishy, Victor, Zahir, Hamim
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6138503/
https://www.ncbi.nlm.nih.gov/pubmed/29920736
http://dx.doi.org/10.1111/bcp.13674

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6138503/
https://www.ncbi.nlm.nih.gov/pubmed/29920736
http://dx.doi.org/10.1111/bcp.13674

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