UPF1-like helicase grip on nucleic acids dictates processivity

Helicases are molecular engines which translocate along nucleic acids (NA) to unwind double-strands or remodel NA–protein complexes. While they have an essential role in genome structure and expression, the rules dictating their processivity remain elusive. Here, we developed single-molecule methods...

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Detalles Bibliográficos
Autores principales: Kanaan, Joanne, Raj, Saurabh, Decourty, Laurence, Saveanu, Cosmin, Croquette, Vincent, Le Hir, Hervé
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6138625/
https://www.ncbi.nlm.nih.gov/pubmed/30218034
http://dx.doi.org/10.1038/s41467-018-06313-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6138625/
https://www.ncbi.nlm.nih.gov/pubmed/30218034
http://dx.doi.org/10.1038/s41467-018-06313-y

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