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Conditional and interaction gene-set analysis reveals novel functional pathways for blood pressure

Gene-set analysis provides insight into which functional and biological properties of genes are aetiologically relevant for a particular phenotype. But genes have multiple properties, and these properties are often correlated across genes. This can cause confounding in a gene-set analysis, because o...

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Detalles Bibliográficos
Autores principales: de Leeuw, Christiaan A., Stringer, Sven, Dekkers, Ilona A., Heskes, Tom, Posthuma, Danielle
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6138636/
https://www.ncbi.nlm.nih.gov/pubmed/30218068
http://dx.doi.org/10.1038/s41467-018-06022-6