A Small Molecule BH3-mimetic Suppresses Cigarette Smoke-Induced Mucous Expression in Airway Epithelial Cells

Cigarette smoke (CS) exposure is one of the primary risk factors associated with the chronic mucous hypersecretion (CMH). The antiapoptotic protein, Bcl-2 sustains hyperplastic mucous cells, and the airway epithelium of ex-smokers with CMH as well as mice exposed to chronic CS showed increased Bcl-2...

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Detalles Bibliográficos
Autores principales: Hussain, Shah S., George, Shebin, Singh, Shashi, Jayant, Rahul, Hu, Chien-An, Sopori, Mohan, Chand, Hitendra S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6138652/
https://www.ncbi.nlm.nih.gov/pubmed/30218002
http://dx.doi.org/10.1038/s41598-018-32114-w

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6138652/
https://www.ncbi.nlm.nih.gov/pubmed/30218002
http://dx.doi.org/10.1038/s41598-018-32114-w

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