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Diminished TLR2-TLR9 mediated CD4+ T cell responses are associated with increased inflammation in intraocular tuberculosis

Intraocular tuberculosis (IOTB) is amongst the leading causes of uveitis in tropical countries. Despite reports on involvement of proinflammatory cytokines, studies on innate immune responses in disease pathogenesis are lacking. Reports from animal models and patients with pulmonary tuberculosis ind...

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Detalles Bibliográficos
Autores principales: Sharma, Ravi Kumar, Sharma, Jyoti, Khan, Zafar K., Pattekar, Ajinkya, Gupta, Vishali, Bansal, Reema, Sharma, Kusum, Aggarwal, Ashutosh Nath, Gupta, Amod, Sachdeva, Naresh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6138653/
https://www.ncbi.nlm.nih.gov/pubmed/30218032
http://dx.doi.org/10.1038/s41598-018-32234-3